CELL BIOLOGY Essay Example | Topics and Well Written Essays - 500 words - 1

CELL BIOLOGY - Essay Example Cholera toxin alters the ÃŽ ± subunit such that the G protein becomes constitutively activated. The result is an increase in cAMP and associated kinases that would amplify the cascade effect and therefore enhance the effect of norepinephrine. If the weaker interaction is still sufficient to activate the receptor but also allows for a faster exchange rate for norepinephrine molecules, then the result would be to enhance the effect of norepinephrine. If, instead, the interaction was not sufficient to activate the receptor, then the effects of norepinephrine would be inhibited because the inactive receptor would not respond to the norepinephrine signal. This will likely inhibit the effects of norepinephrine, because although binding of norepinephrine will still activate the receptor at the same rate, the receptor would no longer be stably associated with the G protein, and the signal will not be transduced from activated receptor to inactive G protein as efficiently. If the ÃŽ ± subunit is responsible for activating adenylate cyclase and signaling an increase in cAMP and activation of resulting cAMP-dependent kinases, then altering the interaction between the ï  ¢Ã¯  § and the protein kinase will have no effect. If instead, the ï  ¢Ã¯  § - protein kinase interaction is necessary for amplification of the norepinephrine signal, then weakening the interaction will have the effect described above (i.e. it will depend on whether or not the weaker interaction is still sufficient to activate the kinase.) ⇒By inhibiting protein phosphatases in general, protein kinases—activated by phosphorylation— and their downstream targets will have longer half lives because phosphatases won’t be available to hydrolyze their phosphate groups. If these kinases and downstream targets are required to potentiate the norepinephrine signal, then the effects of norepinephrine would be enhanced. 2. Receipt of extracellular signals can cause changes in cellular physiology. Some changes

Company Culture and Making the Investment Decisions Assignment

Company Culture and Making the Investment Decisions - Assignment Example It may also affect the performance of the organization. However cultural considerations are taken into account more in case of productive physical resources rather than financial investments. Product/Service Quality This is an essential factor to be taken into consideration while making any investment decision. The quality of the invested capital resources has a direct effect on the quality of the products or services of the organization. The least extensive investment resources would be yielding the lowest quality of products or services for the organization. The manager requires balancing between the quality and the cost for maximizing the cost-effectiveness of the investment. In a similar manner let us consider another example- purchase of the lowest quality of vehicle for the on-site workers would result in the interruptions in fluent or efficient services due to vehicle breakdowns or other related problems. If Laurentian Bakeries Inc. purchases lower quality equipment, it would result in the preparation of low quality food products. Thus the company requires finding a balance between the cost and the quality in order to increase the efficiency of the investment. ... It is very important for the manager of Laurentian Bakeries Inc. to consider the impact that the capital investment decision possess in the environment (Albrecht, 2011). Implementation of strategic plans The strategic plans for the first year of the project are identified to be the operating plan for the same. The operating plan is supported by a detailed list of capital projects which are proposed earlier and thus, becomes the basis for the capital allocation of the project. Initiatives are taken to improve the strategic plans and the benefits associated with the company (Jennings, 2006). The managers are also trained in such a way that they can give out proper instructions to their employees and thus, balance the operation efficiently (Porter, 2011). The corporate strategies are also evaluated in order to acquire the successful projects. The companies are evaluated with regard to the challenges that are being faced by them. The tangible actions have to be linked with the corporate vision so that the projects are successful and yield suitable results. The risk-minimizing factors are also evaluated in order to take the right decision for any project. The quantitative factors that are required for the evaluation of the projects of the company are as follows: 1) Net Present Value: Net present value is the difference in between the present value of the total cash inflow and the present value of the total cash outflow. It helps in determining the value of an investment project thereby facilitating the investment decisions.